Adobe has released a beta of AIR for Linux. Good news, everyone with a 64-bit processor, or PPC, or Sparc, or ARM, or anything more exotic than 32-bit x86. AIR for Linux Release Notes say that all you need is:
Processor - Modern processor (800MHz or faster)
Finally, web applications have freed us from the tyranny of worrying about such difficult issues as endianness, alignment, and struct padding!